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Diacetyl/L-Xylulose Reductase Mediates Chemical Redox Cycling in Lung Epithelial Cells
Reactive carbonyls such as diacetyl (2,3-butanedione) and 2,3-pentanedione in tobacco and many food and consumer products are known to cause severe respiratory diseases. Many of these chemicals are detoxified by carbonyl reductases in the lung, in particular, dicarbonyl/L-xylulose reductase (DCXR),...
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| Udgivet i: | Chem Res Toxicol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5708134/ https://ncbi.nlm.nih.gov/pubmed/28595002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.7b00052 |
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