Загрузка...

Sepiapterin Reductase Mediates Chemical Redox Cycling in Lung Epithelial Cells

In the lung, chemical redox cycling generates highly toxic reactive oxygen species that can cause alveolar inflammation and damage to the epithelium, as well as fibrosis. In this study, we identified a cytosolic NADPH-dependent redox cycling activity in mouse lung epithelial cells as sepiapterin red...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Yang, Shaojun, Jan, Yi-Hua, Gray, Joshua P., Mishin, Vladimir, Heck, Diane E., Laskin, Debra L., Laskin, Jeffrey D.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696693/
https://ncbi.nlm.nih.gov/pubmed/23640889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.402164
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!