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Sepiapterin Reductase Mediates Chemical Redox Cycling in Lung Epithelial Cells
In the lung, chemical redox cycling generates highly toxic reactive oxygen species that can cause alveolar inflammation and damage to the epithelium, as well as fibrosis. In this study, we identified a cytosolic NADPH-dependent redox cycling activity in mouse lung epithelial cells as sepiapterin red...
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| Main Authors: | , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Biochemistry and Molecular Biology
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3696693/ https://ncbi.nlm.nih.gov/pubmed/23640889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.402164 |
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