The enhancer RNA ARIEL activates the oncogenic transcriptional program in T-cell acute lymphoblastic leukemia

The oncogenic transcription factor TAL1 regulates the transcriptional program in T-ALL. ARID5B is one of the critical downstream targets of TAL1, which further activates the oncogenic regulatory circuit in T-ALL cells. Here, we elucidated the molecular functions of the noncoding RNA, ARID5B-inducing...

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Bibliografiske detaljer
Udgivet i:Blood
Main Authors: Tan, Shi Hao, Leong, Wei Zhong, Ngoc, Phuong Cao Thi, Tan, Tze King, Bertulfo, Fatima Carla, Lim, Mei Chee, An, Omer, Li, Zhenhua, Yeoh, Allen Eng Juh, Fullwood, Melissa J., Tenen, Daniel G., Sanda, Takaomi
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2019
Fag:
Lymphoid Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8212351/
https://ncbi.nlm.nih.gov/pubmed/31076442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2018874503
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