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Aberrant Activation of the GIMAP Enhancer by Oncogenic Transcription Factors in T-cell Acute Lymphoblastic Leukemia
The transcription factor TAL1/SCL is one of the most prevalent oncogenes in T-cell acute lymphoblastic leukemia (T-ALL), a malignant disorder resulting from leukemic transformation of thymus T-cell precursors. TAL1 is normally expressed in hematopoietic stem cells (HSCs) but is silenced in immature...
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| 出版年: | Leukemia |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5529293/ https://ncbi.nlm.nih.gov/pubmed/28028313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2016.392 |
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