Oncorequisite role of an aldehyde dehydrogenase in the pathogenesis of T-cell acute lymphoblastic leukemia

Aldehyde dehydrogenases (ALDH) are overexpressed in various types of cancers. One of the ALDH family genes, ALDH1A2, is aberrantly expressed in more than 50% of cases of T-cell acute lymphoblastic leukemia (T-ALL). However, its molecular function and role in the pathogenesis of T-ALL are largely unk...

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Détails bibliographiques
Publié dans:Haematologica
Auteurs principaux: Zhang, Chujing, Amanda, Stella, Wang, Cheng, Tan, Tze King, Ali, Muhammad Zulfaqar, Leong, Wei Zhong, Ng, Ley Moy, Kitajima, Shojiro, Li, Zhenhua, Yeoh, Allen Eng Juh, Tan, Shi Hao, Sanda, Takaomi
Format: Artigo
Langue:Inglês
Publié: Fondazione Ferrata Storti 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168519/
https://ncbi.nlm.nih.gov/pubmed/32414855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.245639
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