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GLT1 gene delivery based on bone marrow-derived cells ameliorates motor function and survival in a mouse model of ALS
Amyotrophic lateral sclerosis (ALS) is an intractable neurodegenerative disease. CD68-positive bone marrow (BM)-derived cells (BMDCs) accumulate in the pathological lesion in the SOD1(G93A) ALS mouse model after BM transplantation (BMT). Therefore, we investigated whether BMDCs can be applied as gen...
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| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8211665/ https://ncbi.nlm.nih.gov/pubmed/34140581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-92285-x |
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