Advanced Technology for Gene Delivery with Homing Peptides to Spinal Cord through Systemic Circulation in Mice

Homing peptides to the spinal cord were identified and isolated using phage display technology. In vivo biopanning was performed by intravenous systemic injection of a phage library to screen specific peptides targeting the spinal cord of mice. Analyses of the sequences of targeted phages yielded tw...

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Bibliografiske detaljer
Udgivet i:Mol Ther Methods Clin Dev
Main Authors: Terashima, Tomoya, Ogawa, Nobuhiro, Sato, Toshiyuki, Katagi, Miwako, Nakae, Yuki, Okano, Junko, Maegawa, Hiroshi, Kojima, Hideto
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538929/
https://ncbi.nlm.nih.gov/pubmed/31193742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2019.04.008
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