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Transplantation of M2-Deviated Microglia Promotes Recovery of Motor Function after Spinal Cord Injury in Mice

Despite the poor prognosis of spinal cord injury (SCI), effective treatments are lacking. Diverse factors regulate SCI prognosis. In this regard, microglia play crucial roles depending on their phenotype. The M1 phenotype exacerbates neuroinflammation, whereas the M2 phenotype promotes tissue repair...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Kobashi, Shuhei, Terashima, Tomoya, Katagi, Miwako, Nakae, Yuki, Okano, Junko, Suzuki, Yoshihisa, Urushitani, Makoto, Kojima, Hideto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952178/
https://ncbi.nlm.nih.gov/pubmed/31604678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.09.004
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