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Fever During Localized Inflammation in Mice Is Elicited by a Humoral Pathway and Depends on Brain Endothelial Interleukin-1 and Interleukin-6 Signaling and Central EP(3) Receptors

We examined the signaling route for fever during localized inflammation in male and female mice, elicited by casein injection into a preformed air pouch. The localized inflammation gave rise to high concentrations of prostaglandins of the E species (PGE(2)) and cytokines in the air pouch and elevate...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Eskilsson, Anna, Shionoya, Kiseko, Engblom, David, Blomqvist, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8211540/
https://ncbi.nlm.nih.gov/pubmed/33941650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0313-21.2021
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