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Cereblon Regulates the Proteotoxicity of Tau by Tuning the Chaperone Activity of DNAJA1
Protein aggregation can induce explicit neurotoxic events that trigger a number of presently untreatable neurodegenerative disorders. Chaperones, on the other hand, play a neuroprotective role because of their ability to unfold and refold abnormal proteins. The progressive nature of neurotoxic event...
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| 出版年: | J Neurosci |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Society for Neuroscience
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8211538/ https://ncbi.nlm.nih.gov/pubmed/33972400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2494-20.2021 |
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