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Strain-Specific Peptide (SSP) Interference Reference Sample: A Genetically Encoded Quality Control for Isobaric Tagging Strategies

Isobaric tag-based sample multiplexing strategies are extensively used for global protein abundance profiling. However, such analyses are often confounded by ratio compression resulting from the co-isolation, co-fragmentation, and co-quantification of co-eluting peptides, termed “interference.” Rece...

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Détails bibliographiques
Publié dans:Anal Chem
Auteurs principaux: Zhang, Tian, Keele, Greg R., Churchill, Gary A., Gygi, Steven P., Paulo, Joao A.
Format: Artigo
Langue:Inglês
Publié: 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8210951/
https://ncbi.nlm.nih.gov/pubmed/33735571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.0c05483
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