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A Triple Knockout (TKO) Proteomics Standard for Diagnosing Ion Interference in Isobaric Labeling Experiments

Isobaric labeling is a powerful strategy for quantitative mass spectrometry-based proteomic investigations. A complication of such analyses has been the co-isolation of multiple analytes of similar mass-to-charge resulting in the distortion of relative protein abundance measurements across samples....

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Detalhes bibliográficos
Publicado no:J Am Soc Mass Spectrom
Main Authors: Paulo, Joao A., O'Connell, Jeremy D., Gygi, Steven P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018445/
https://ncbi.nlm.nih.gov/pubmed/27400695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-016-1434-9
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