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HYpro16: A Two-Proteome Mixture to Assess Interference in Isobaric Tag-Based Sample Multiplexing Experiments

Isobaric tagging is a powerful strategy for global proteome profiling. A caveat of isobaric-tag-based quantification is “interference”, which may be caused by coeluting peptides that are coisolated, cofragmented, and coanalyzed, thereby confounding quantitative accuracy. Here, we present a two-prote...

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Detalles Bibliográficos
Publicado en:J Am Soc Mass Spectrom
Main Authors: Navarrete-Perea, Jose, Gygi, Steven P., Paulo, Joao A.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8210950/
https://ncbi.nlm.nih.gov/pubmed/33175540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jasms.0c00299
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