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Creutzfeldt–Jakob disease in pregnancy: the use of modified RT-QuIC to determine infectivity in placental tissues

Sporadic Creutzfeldt–Jakob Disease (sCJD) rarely affects women of childbearing age. There is currently no evidence of vertical transmission. Given the biosafety implications of performing Caesarean sections (C-section) in these patients, we used sensitive real-time quaking-induced conversion (RT-QuI...

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Udgivet i:Prion
Main Authors: Luk, Collin C., Mathiason, Candace K., Orrù, Christina D., Jansen, Gerard H., Thiele, Allison, Caughey, Byron, Sim, Valerie L.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8210859/
https://ncbi.nlm.nih.gov/pubmed/34132175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2021.1933872
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