RT-QuIC analysis of cerebrospinal fluid in sporadic Creutzfeldt-Jakob disease

OBJECTIVE: Current cerebrospinal fluid (CSF) tests for sporadic Creutzfeldt-Jakob disease (sCJD) are based on the detection of surrogate markers of neuronal damage such as CSF 14-3-3 which are not specific for sCJD. A number of prion protein conversion assays have been developed, including real-time...

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Hauptverfasser: McGuire, Lynne I., Peden, Alexander H., Orrú, Christina D., Wilham, Jason M., Appleford, Nigel E., Mallinson, Gary, Andrews, Mary, Head, Mark W., Caughey, Byron, Will, Robert G., Knight, Richard S.G., Green, Alison J.E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458796/
https://ncbi.nlm.nih.gov/pubmed/22926858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.23589
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