Stability and Reproducibility Underscore Utility of RT-QuIC for Diagnosis of Creutzfeldt-Jakob Disease

Real-time quaking-induced conversion (RT-QuIC) allows the amplification of miniscule amounts of scrapie prion protein (PrP(Sc)). Recent studies applied the RT-QuIC methodology to cerebrospinal fluid (CSF) for diagnosing human prion diseases. However, to date, there has not been a formal multi-centre...

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Publicat a:Mol Neurobiol
Autors principals: Cramm, Maria, Schmitz, Matthias, Karch, André, Mitrova, Eva, Kuhn, Franziska, Schroeder, Bjoern, Raeber, Alex, Varges, Daniela, Kim, Yong-Sun, Satoh, Katsuya, Collins, Steven, Zerr, Inga
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789202/
https://ncbi.nlm.nih.gov/pubmed/25823511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-015-9133-2
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