Increased susceptibility to dextran sulfate-induced mucositis of iron-overload β-thalassemia mice, another endogenous cause of septicemia in thalassemia

Enterocyte damage and gut dysbiosis are caused by iron-overload in thalassemia (Thl), possibly making the gut vulnerable to additional injury. Hence, iron-overload in the heterozygous β-globin deficient (Hbb(th3/+)) mice were tested with 3% dextran sulfate solution (DSS). With 4 months of iron-gavag...

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Détails bibliographiques
Publié dans:Clin Sci (Lond)
Auteurs principaux: Visitchanakun, Peerapat, Panpetch, Wimonrat, Saisorn, Wilasinee, Chatthanathon, Piraya, Wannigama, Dhammika Leshan, Thim-uam, Arthid, Svasti, Saovaros, Fucharoen, Suthat, Somboonna, Naraporn, Leelahavanichkul, Asada
Format: Artigo
Langue:Inglês
Publié: Portland Press Ltd. 2021
Sujets:
Immunology & Inflammation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209035/
https://ncbi.nlm.nih.gov/pubmed/34131711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20210328
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