Pathogen-Associated Molecules from Gut Translocation Enhance Severity of Cecal Ligation and Puncture Sepsis in Iron-Overload β-Thalassemia Mice

INTRODUCTION: Systemic inflammation induced by gut translocation of lipopolysaccharide (LPS), a major component of Gram-negative bacteria, in thalassemia with iron-overload worsens sepsis. However, the impact of (1→3)-β-D-glucan (BG), a major fungal molecule, in iron-overload thalassemia is still un...

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Detalles Bibliográficos
Publicado en:J Inflamm Res
Main Authors: Sae-khow, Kritsanawan, Charoensappakit, Awirut, Visitchanakun, Peerapat, Saisorn, Wilasinee, Svasti, Saovaros, Fucharoen, Suthat, Leelahavanichkul, Asada
Formato: Artigo
Idioma:Inglês
Publicado: Dove 2020
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7569041/
https://ncbi.nlm.nih.gov/pubmed/33116751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JIR.S273329
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