Lipopolysaccharide-Enhanced Responses against Aryl Hydrocarbon Receptor in FcgRIIb-Deficient Macrophages, a Profound Impact of an Environmental Toxin on a Lupus-Like Mouse Model

Fc gamma receptor IIb (FcgRIIb) is the only inhibitory-FcgR in the FcgR family, and FcgRIIb-deficient (FcgRIIb(−/−)) mice develop a lupus-like condition with hyper-responsiveness against several stimulations. The activation of aryl hydrocarbon receptor (Ahr), a cellular environmental sensor, might a...

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Bibliografiska uppgifter
I publikationen:Int J Mol Sci
Huvudupphovsmän: Udompornpitak, Kanyarat, Bhunyakarnjanarat, Thansita, Charoensappakit, Awirut, Dang, Cong Phi, Saisorn, Wilasinee, Leelahavanichkul, Asada
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2021
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073880/
https://ncbi.nlm.nih.gov/pubmed/33919603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22084199
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