Lipopolysaccharide-Enhanced Responses against Aryl Hydrocarbon Receptor in FcgRIIb-Deficient Macrophages, a Profound Impact of an Environmental Toxin on a Lupus-Like Mouse Model

Fc gamma receptor IIb (FcgRIIb) is the only inhibitory-FcgR in the FcgR family, and FcgRIIb-deficient (FcgRIIb(−/−)) mice develop a lupus-like condition with hyper-responsiveness against several stimulations. The activation of aryl hydrocarbon receptor (Ahr), a cellular environmental sensor, might a...

Full description

Saved in:
Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Udompornpitak, Kanyarat, Bhunyakarnjanarat, Thansita, Charoensappakit, Awirut, Dang, Cong Phi, Saisorn, Wilasinee, Leelahavanichkul, Asada
Format: Artigo
Language:Inglês
Published: MDPI 2021
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073880/
https://ncbi.nlm.nih.gov/pubmed/33919603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22084199
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items