Pharmacological inhibition of thioredoxin reductase increases insulin secretion and diminishes beta cell viability

Apparently, both a decrease in beta cell function and in beta cell mass contribute to the progressive worsening of type 2 diabetes. So, it is of particular interest to define factors which are relevant for the regulation of insulin secretion and at the same time for the maintenance of beta cell mass...

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Detaylı Bibliyografya
Yayımlandı:Naunyn Schmiedebergs Arch Pharmacol
Asıl Yazarlar: Brüning, Dennis, Hatlapatka, Kathrin, Lier-Glaubitz, Verena, Andermark, Vincent, Scherneck, Stephan, Ott, Ingo, Rustenbeck, Ingo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer Berlin Heidelberg 2021
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8208932/
https://ncbi.nlm.nih.gov/pubmed/33464387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-020-02046-2
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