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Thioredoxin Reductase Is Essential for Viability in the Fungal Pathogen Cryptococcus neoformans

Thioredoxin reductase (TRR1) is an important component of the thioredoxin oxidative stress resistance pathway. Here we show that it is induced during oxidative and nitrosative stress and is preferentially localized to the mitochondria in Cryptococcus neoformans. The C. neoformans TRR1 gene encodes t...

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Detalhes bibliográficos
Main Authors: Missall, Tricia A., Lodge, Jennifer K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC549343/
https://ncbi.nlm.nih.gov/pubmed/15701811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.4.2.487-489.2005
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