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Thioredoxin Reductase Is Essential for Viability in the Fungal Pathogen Cryptococcus neoformans

Thioredoxin reductase (TRR1) is an important component of the thioredoxin oxidative stress resistance pathway. Here we show that it is induced during oxidative and nitrosative stress and is preferentially localized to the mitochondria in Cryptococcus neoformans. The C. neoformans TRR1 gene encodes t...

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Bibliografiske detaljer
Main Authors: Missall, Tricia A., Lodge, Jennifer K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC549343/
https://ncbi.nlm.nih.gov/pubmed/15701811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.4.2.487-489.2005
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