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Palladium/Xu-Phos-catalyzed asymmetric carboamination towards isoxazolidines and pyrrolidines
An efficient palladium-catalyzed enantioselective carboamination reaction of N-Boc-O-homoallyl-hydroxylamines and N-Boc-pent-4-enylamines with aryl or alkenyl bromides was developed, delivering various substituted isoxazolidines and pyrrolidines in good yields with up to 97% ee. The reaction feature...
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| Publicado en: | Chem Sci |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Royal Society of Chemistry
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8208297/ https://ncbi.nlm.nih.gov/pubmed/34194715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1sc01337h |
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