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Palladium-Catalyzed Tandem N-Arylation/Carboamination Reactions for the Stereoselective Synthesis of N-Aryl-2-Benzyl Pyrrolidines

[Image: see text] The tandem N-arylation/carboamination of γ-amino alkenes with two different aryl bromides provides rapid entry to differentially arylated N-aryl-2-benzyl pyrrolidine derivatives in good yields with good to excellent levels of diastereoselectivity. The selective diarylation is achie...

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Autors principals: Yang, Qifei, Ney, Joshua E., Wolfe, John P.
Format: Artigo
Idioma:Inglês
Publicat: 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750836/
https://ncbi.nlm.nih.gov/pubmed/15957894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol050647u
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