Divergent camptothecin biosynthetic pathway in Ophiorrhiza pumila

BACKGROUND: The anticancer drug camptothecin (CPT), first isolated from Camptotheca acuminata, was subsequently discovered in unrelated plants, including Ophiorrhiza pumila. Unlike known monoterpene indole alkaloids, CPT in C. acuminata is biosynthesized via the key intermediate strictosidinic acid,...

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書誌詳細
出版年:BMC Biol
主要な著者: Yang, Mengquan, Wang, Qiang, Liu, Yining, Hao, Xiaolong, Wang, Can, Liang, Yuchen, Chen, Jianbo, Xiao, Youli, Kai, Guoyin
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2021
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8207662/
https://ncbi.nlm.nih.gov/pubmed/34134716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-021-01051-y
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