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The transcription factor OpWRKY2 positively regulates the biosynthesis of the anticancer drug camptothecin in Ophiorrhiza pumila

The limited bioavailability of plant-derived natural products with anticancer activity poses major challenges to the pharmaceutical industry. An example of this is camptothecin, a monoterpene indole alkaloid with potent anticancer activity that is extracted at very low concentrations from woody plan...

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Detalhes bibliográficos
Publicado no:Hortic Res
Main Authors: Hao, Xiaolong, Xie, Chenhong, Ruan, Qingyan, Zhang, Xichen, Wu, Chao, Han, Bing, Qian, Jun, Zhou, Wei, Nützmann, Hans-Wilhelm, Kai, Guoyin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7775441/
https://ncbi.nlm.nih.gov/pubmed/33384421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41438-020-00437-3
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