Ubiquitin E3 ligase MID1 inhibits the innate immune response by ubiquitinating IRF3

Interferon regulatory factor 3 (IRF3) is a critical transcription factor for inducing production of type I interferons (IFN‐I) and regulating host antiviral response. Although IRF3 activation during viral infection has been extensively studied, the inhibitory regulation of IRF3 remains largely unexp...

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Pubblicato in:Immunology
Autori principali: Chen, Xiangjie, Xu, Ying, Tu, Wenhui, Huang, Fan, Zuo, Yibo, Zhang, Hong‐Guang, Jin, Lincong, Feng, Qian, Ren, Tengfei, He, Jiuyi, Miao, Ying, Yuan, Yukang, Zhao, Qian, Liu, Jiapeng, Zhang, Renxia, Zhu, Li, Qian, Feng, Zhu, Chuanwu, Zheng, Hui, Wang, Jun
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8207362/
https://ncbi.nlm.nih.gov/pubmed/33513265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13315
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