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Potential 3‐chymotrypsin‐like cysteine protease cleavage sites in the coronavirus polyproteins pp1a and pp1ab and their possible relevance to COVID‐19 vaccine and drug development
Coronavirus (CoV) 3‐chymotrypsin (C)‐like cysteine protease (3CL(pro)) is a target for anti‐CoV drug development and drug repurposing because along with papain‐like protease, it cleaves CoV‐encoded polyproteins (pp1a and pp1ab) into nonstructural proteins (nsps) for viral replication. However, the c...
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| Publicado no: | FASEB J |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8206714/ https://ncbi.nlm.nih.gov/pubmed/33913206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202100280RR |
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