Arterivirus nsp12 versus the coronavirus nsp16 2′-O-methyltransferase: comparison of the C-terminal cleavage products of two nidovirus pp1ab polyproteins

The 3′-terminal domain of the most conserved ORF1b in three of the four families of the order Nidovirales (except for the family Arteriviridae) encodes a (putative) 2′-O-methyltransferase (2′-O-MTase), known as non structural protein (nsp) 16 in the family Coronaviridae and implicated in methylation...

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Detalhes bibliográficos
Publicado no:J Gen Virol
Main Authors: Lehmann, Kathleen C., Hooghiemstra, Lisa, Gulyaeva, Anastasia, Samborskiy, Dmitry V., Zevenhoven-Dobbe, Jessika C., Snijder, Eric J., Gorbalenya, Alexander E., Posthuma, Clara C.
Formato: Artigo
Idioma:Inglês
Publicado em: Microbiology Society 2015
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Standard
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081073/
https://ncbi.nlm.nih.gov/pubmed/26041874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.000209
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