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Binding of HIV-1 virions to α(4)β(7) expressing cells and impact of antagonizing α(4)β(7) on HIV-1 infection of primary CD4(+) T cells

HIV-1 envelope glycoprotein is reported to interact with α(4)β(7), an integrin mediating the homing of lymphocytes to gut-associated lymphoid tissue, but the significance of α(4)β(7) in HIV-1 infection remains controversial. Here, using HIV-1 strain BaL, the gp120 of which was previously shown to be...

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Detalhes bibliográficos
Publicado no:Virol Sin
Main Authors: Li, Chang, Jin, Wei, Du, Tao, Wu, Biao, Liu, Yalan, Shattock, Robin J., Hu, Qinxue
Formato: Artigo
Idioma:Inglês
Publicado em: Wuhan Institute of Virology, CAS 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8206286/
https://ncbi.nlm.nih.gov/pubmed/25527342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12250-014-3525-8
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