Glycosylation and oligomeric state of envelope protein might influence HIV-1 virion capture by α4β7 integrin

The α4β7 integrin present on host cells recognizes the V1V2 domain of the HIV-1 envelope protein. This interaction might be involved in virus transmission. Administration of α4β7-specific antibodies inhibit acquisition of SIV in a macaque challenge model. But the molecular details of V1V2:α4β7 inter...

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Bibliographic Details
Published in:Virology
Main Authors: Chand, Subhash, Messina, Emily L, AlSalmi, Wadad, Ananthaswamy, Neeti, Gao, Guofen, Uritskiy, Gherman, Padilla-Sanchez, Victor, Mahalingam, Marthandan, Peachman, Kristina K., Robb, Merlin L, Rao, Mangala, Rao, Venigalla B
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526109/
https://ncbi.nlm.nih.gov/pubmed/28577856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2017.05.016
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