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Quantitative Analyses Reveal Distinct Sensitivities of the Capture of HIV-1 Primary Viruses and Pseudoviruses to Broadly Neutralizing Antibodies

Development of vaccines capable of eliciting broadly neutralizing antibodies (bNAbs) is a key goal to controlling the global AIDS epidemic. To be effective, bNAbs must block the capture of HIV-1 to prevent viral acquisition and establishment of reservoirs. However, the role of bNAbs, particularly du...

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Publicado en:Virology
Main Authors: Kim, Jiae, Jobe, Ousman, Peachman, Kristina K., Michael, Nelson L., Robb, Merlin L., Rao, Mangala, Rao, Venigalla B.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531191/
https://ncbi.nlm.nih.gov/pubmed/28577855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2017.05.015
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