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Computational Evaluation of Interaction Between Curcumin Derivatives and Amyloid-β Monomers and Fibrils: Relevance to Alzheimer’s Disease

BACKGROUND: The most important hallmark in the neuropathology of Alzheimer’s disease (AD) is the formation of amyloid-β (Aβ) fibrils due to the misfolding/aggregation of the Aβ peptide. Preventing or reverting the aggregation process has been an active area of research. Naturally occurring products...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Orjuela, Adrian, Lakey-Beitia, Johant, Mojica-Flores, Randy, Hegde, Muralidhar L., Lans, Isaias, Alí-Torres, Jorge, Rao, K.S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8206224/
https://ncbi.nlm.nih.gov/pubmed/33337368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-200941
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