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Quantifying the contribution of dominance deviation effects to complex trait variation in biobank-scale data

The proportion of variation in complex traits that can be attributed to non-additive genetic effects has been a topic of intense debate. The availability of biobank-scale datasets of genotype and trait data from unrelated individuals opens up the possibility of obtaining precise estimates of the con...

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Detalles Bibliográficos
Publicado en:Am J Hum Genet
Autores principales: Pazokitoroudi, Ali, Chiu, Alec M., Burch, Kathryn S., Pasaniuc, Bogdan, Sankararaman, Sriram
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8206203/
https://ncbi.nlm.nih.gov/pubmed/33811807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2021.03.018
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