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A unifying framework for joint trait analysis under a non-infinitesimal model
MOTIVATION: A large proportion of risk regions identified by genome-wide association studies (GWAS) are shared across multiple diseases and traits. Understanding whether this clustering is due to sharing of causal variants or chance colocalization can provide insights into shared etiology of complex...
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| Veröffentlicht in: | Bioinformatics |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6022541/ https://ncbi.nlm.nih.gov/pubmed/29949958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty254 |
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