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A unifying framework for joint trait analysis under a non-infinitesimal model

MOTIVATION: A large proportion of risk regions identified by genome-wide association studies (GWAS) are shared across multiple diseases and traits. Understanding whether this clustering is due to sharing of causal variants or chance colocalization can provide insights into shared etiology of complex...

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Vydáno v:Bioinformatics
Hlavní autoři: Johnson, Ruth, Shi, Huwenbo, Pasaniuc, Bogdan, Sankararaman, Sriram
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022541/
https://ncbi.nlm.nih.gov/pubmed/29949958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty254
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