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Integrated analysis of Xist upregulation and X-chromosome inactivation with single-cell and single-allele resolution
To ensure dosage compensation between the sexes, one randomly chosen X chromosome is silenced in each female cell in the process of X-chromosome inactivation (XCI). XCI is initiated during early development through upregulation of the long non-coding RNA Xist, which mediates chromosome-wide gene sil...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8206119/ https://ncbi.nlm.nih.gov/pubmed/34131144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23643-6 |
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