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Generation of a new mouse line with conditionally activated signaling through the BMP receptor, ACVR1: A tool to characterize pleiotropic roles of BMP functions

BMP signaling plays pleiotropic roles in various tissues during embryogenesis and after birth. We have previously generated a constitutively activated Acvr1(ca-Acvr1) transgenic mouse line (line L35) through pronuclei injection to investigate impacts of enhanced BMP signaling in a tissue specific ma...

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Bibliografiske detaljer
Udgivet i:Genesis
Main Authors: Yang, Jingwen, Nakamura, Masako Toda, Hallett, Shawn A., Ueharu, Hiroki, Zhang, Honghao, Kelley, Kristen, Fukuda, Tomokazu, Komatsu, Yoshihiro, Mishina, Yuji
Format: Artigo
Sprog:Inglês
Udgivet: 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8206043/
https://ncbi.nlm.nih.gov/pubmed/33851764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.23419
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