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Constitutively active mutation of ACVR1 in oral epithelium causes submucous cleft palate in mice

Cleft palate is among the most common human birth defects. Submucous cleft palate (SMCP) is a subgroup of cleft palate, which may be as common as overt cleft palate. Despite the high frequency of SMCP in humans, only recently have several animal models of SMCP begun to provide insight into the mecha...

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Detalhes bibliográficos
Publicado no:Dev Biol
Main Authors: Noda, Kazuo, Mishina, Yuji, Komatsu, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4689666/
https://ncbi.nlm.nih.gov/pubmed/26116174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2015.06.014
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