Identifying the Lipidomic Effects of a Rare Loss-of-Function Deletion in ANGPTL3

BACKGROUND: The identification and understanding of therapeutic targets for atherosclerotic cardiovascular disease (ASCVD) is of fundamental importance given its global health and economic burden. Inhibition of angiopoietin-like 3 (ANGPTL3) has demonstrated a cardioprotective effect, showing promise...

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Detalhes bibliográficos
Publicado no:Circ Genom Precis Med
Main Authors: Blackburn, Nicholas B., Meikle, Peter J., Peralta, Juan M., Kumar, Satish, Leandro, Ana C., Bellinger, Melissa A., Giles, Corey, Huynh, Kevin, Mahaney, Michael C., Göring, Harald H. H., VandeBerg, John L., Williams-Blangero, Sarah, Glahn, David C., Duggirala, Ravindranath, Blangero, John, Michael, Laura F., Curran, Joanne E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8206021/
https://ncbi.nlm.nih.gov/pubmed/33887960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGEN.120.003232
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