Identifying the Lipidomic Effects of a Rare Loss-of-Function Deletion in ANGPTL3

BACKGROUND: The identification and understanding of therapeutic targets for atherosclerotic cardiovascular disease (ASCVD) is of fundamental importance given its global health and economic burden. Inhibition of angiopoietin-like 3 (ANGPTL3) has demonstrated a cardioprotective effect, showing promise...

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Détails bibliographiques
Publié dans:Circ Genom Precis Med
Auteurs principaux: Blackburn, Nicholas B., Meikle, Peter J., Peralta, Juan M., Kumar, Satish, Leandro, Ana C., Bellinger, Melissa A., Giles, Corey, Huynh, Kevin, Mahaney, Michael C., Göring, Harald H. H., VandeBerg, John L., Williams-Blangero, Sarah, Glahn, David C., Duggirala, Ravindranath, Blangero, John, Michael, Laura F., Curran, Joanne E.
Format: Artigo
Langue:Inglês
Publié: 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8206021/
https://ncbi.nlm.nih.gov/pubmed/33887960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGEN.120.003232
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