Identifying the Lipidomic Effects of a Rare Loss-of-Function Deletion in ANGPTL3

BACKGROUND: The identification and understanding of therapeutic targets for atherosclerotic cardiovascular disease (ASCVD) is of fundamental importance given its global health and economic burden. Inhibition of angiopoietin-like 3 (ANGPTL3) has demonstrated a cardioprotective effect, showing promise...

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Dades bibliogràfiques
Publicat a:Circ Genom Precis Med
Autors principals: Blackburn, Nicholas B., Meikle, Peter J., Peralta, Juan M., Kumar, Satish, Leandro, Ana C., Bellinger, Melissa A., Giles, Corey, Huynh, Kevin, Mahaney, Michael C., Göring, Harald H. H., VandeBerg, John L., Williams-Blangero, Sarah, Glahn, David C., Duggirala, Ravindranath, Blangero, John, Michael, Laura F., Curran, Joanne E.
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8206021/
https://ncbi.nlm.nih.gov/pubmed/33887960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGEN.120.003232
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