Chimeric Zika viruses containing structural protein genes of insect-specific flaviviruses cannot replicate in vertebrate cells due to entry and post-translational restrictions

Long Pine Key virus (LPKV) and Lammi virus are insect-specific flaviviruses that phylogenetically affiliate with dual-host flaviviruses. The goal of this study was to provide insight into the genetic determinants that condition this host range restriction. Chimeras were initially created by replacin...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Virology
Autores principales: Tangudu, Chandra S., Charles, Jermilia, Nunez-Avellaneda, Daniel, Hargett, Alissa M., Brault, Aaron C., Blitvich, Bradley J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2021
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205982/
https://ncbi.nlm.nih.gov/pubmed/33812340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2021.03.014
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares