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Chimeric Zika viruses containing structural protein genes of insect-specific flaviviruses cannot replicate in vertebrate cells due to entry and post-translational restrictions

Long Pine Key virus (LPKV) and Lammi virus are insect-specific flaviviruses that phylogenetically affiliate with dual-host flaviviruses. The goal of this study was to provide insight into the genetic determinants that condition this host range restriction. Chimeras were initially created by replacin...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Virology
Κύριοι συγγραφείς: Tangudu, Chandra S., Charles, Jermilia, Nunez-Avellaneda, Daniel, Hargett, Alissa M., Brault, Aaron C., Blitvich, Bradley J.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2021
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205982/
https://ncbi.nlm.nih.gov/pubmed/33812340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2021.03.014
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