Structural basis for the coiled-coil architecture of human CtIP

The DNA repair factor CtIP has a critical function in double-strand break (DSB) repair by homologous recombination, promoting the assembly of the repair apparatus at DNA ends and participating in DNA-end resection. However, the molecular mechanisms of CtIP function in DSB repair remain unclear. Here...

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Bibliografiske detaljer
Udgivet i:Open Biol
Main Authors: Morton, C. R., Rzechorzek, N. J., Maman, J. D., Kuramochi, M., Sekiguchi, H., Rambo, R., Sasaki, Y. C., Davies, O. R., Pellegrini, L.
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205527/
https://ncbi.nlm.nih.gov/pubmed/34129781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.210060
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