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Finding Treatment Effects in Alzheimer Trials in the Face of Disease Progression Heterogeneity
OBJECTIVE: To investigate the influence of heterogeneity in disease progression for detecting treatment effects in Alzheimer disease (AD) trials, using a simulation study. METHODS: Individuals with an abnormal amyloid PET scan, diagnosis of mild cognitive impairment or dementia, baseline Mini-Mental...
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| Yayımlandı: | Neurology |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Lippincott Williams & Wilkins
2021
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8205463/ https://ncbi.nlm.nih.gov/pubmed/34550903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000012022 |
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