Modeling grey matter atrophy as a function of time, aging or cognitive decline show different anatomical patterns in Alzheimer's disease

BACKGROUND: Grey matter (GM) atrophy in Alzheimer's disease (AD) is most commonly modeled as a function of time. However, this approach does not take into account inter-individual differences in initial disease severity or changes due to aging. Here, we modeled GM atrophy within individuals acr...

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Pubblicato in:Neuroimage Clin
Autori principali: Dicks, Ellen, Vermunt, Lisa, van der Flier, Wiesje M., Visser, Pieter Jelle, Barkhof, Frederik, Scheltens, Philip, Tijms, Betty M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
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Regular Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6439228/
https://ncbi.nlm.nih.gov/pubmed/30921610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2019.101786
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