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Drug release testing of long-acting intrauterine systems

Performance evaluation of polydimethylsiloxane (PDMS) based long-acting (e.g. 3–5 years) levonorgestrel (LNG) intrauterine systems (IUSs), such as Mirena(®), is challenging due to their complex formulation, locally-acting feature, and extremely long duration of drug release. To achieve such long-ter...

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Détails bibliographiques
Publié dans:J Control Release
Auteurs principaux: Bao, Quanying, Zou, Yuan, Wang, Yan, Kozak, Darby, Choi, Stephanie, Burgess, Diane J.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205262/
https://ncbi.nlm.nih.gov/pubmed/31733294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2019.11.015
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