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Impact of product design parameters on in vitro release from intrauterine systems

Polydimethylsiloxane (PDMS)-based levonorgestrel intrauterine systems (LNG-IUSs) contain a large amount of potent LNG, and therefore it is important to understand the impact of product design parameters on the in vitro and in vivo performance to ensure safety and efficacy, as well as to avoid seriou...

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Detalhes bibliográficos
Publicado no:Int J Pharm
Main Authors: Bao, Quanying, Zou, Yuan, Wang, Yan, Choi, Stephanie, Burgess, Diane J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8220931/
https://ncbi.nlm.nih.gov/pubmed/32057890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2020.119135
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