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Impact of product design parameters on in vitro release from intrauterine systems

Polydimethylsiloxane (PDMS)-based levonorgestrel intrauterine systems (LNG-IUSs) contain a large amount of potent LNG, and therefore it is important to understand the impact of product design parameters on the in vitro and in vivo performance to ensure safety and efficacy, as well as to avoid seriou...

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Detalles Bibliográficos
Publicado en:Int J Pharm
Autores principales: Bao, Quanying, Zou, Yuan, Wang, Yan, Choi, Stephanie, Burgess, Diane J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8220931/
https://ncbi.nlm.nih.gov/pubmed/32057890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2020.119135
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