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Manufacturing and characterization of long-acting levonorgestrel intrauterine systems

Mirena® is long-acting (5 years) contraceptive intrauterine device. It is composed of a hollow cylindrical drug reservoir (containing Levonorgestrel and polydimethylsiloxane), which is covered with a release rate controlling silicone membrane. This structure presents a manufacturing challenge and to...

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Bibliografiska uppgifter
I publikationen:Int J Pharm
Huvudupphovsmän: Bao, Quanying, Gu, Bing, Price, Claire F., Zou, Yuan, Wang, Yan, Kozak, Darby, Choi, Stephanie, Burgess, Diane J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6622171/
https://ncbi.nlm.nih.gov/pubmed/30195080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2018.09.004
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