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Manufacturing and characterization of long-acting levonorgestrel intrauterine systems
Mirena® is long-acting (5 years) contraceptive intrauterine device. It is composed of a hollow cylindrical drug reservoir (containing Levonorgestrel and polydimethylsiloxane), which is covered with a release rate controlling silicone membrane. This structure presents a manufacturing challenge and to...
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| Publicado no: | Int J Pharm |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6622171/ https://ncbi.nlm.nih.gov/pubmed/30195080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2018.09.004 |
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