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Phenolic Preservative Removal from Commercial Insulin Formulations Reduces Tissue Inflammation while Maintaining Euglycemia

[Image: see text] Background: Exogenous insulin therapy requires stabilization of the insulin molecule, which is achieved through the use of excipients (e.g., phenolic preservatives (PP)) that provide protein stability, sterility and prolong insulin shelf life. However, our laboratory recently repor...

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Detalhes bibliográficos
Publicado no:ACS Pharmacol Transl Sci
Main Authors: Mulka, Adam, Lewis, Brianne E., Mao, Li, Sharafieh, Roshanak, Kesserwan, Shereen, Wu, Rong, Kreutzer, Donald L., Klueh, Ulrike
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205237/
https://ncbi.nlm.nih.gov/pubmed/34151206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.1c00047
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